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Synthesis of enantiopure fluorinated ceramides; Analogues of natural sphingolipids
Authors:
- Katarzyna Koroniak-Szejn,
- Günter Haufe
Abstract
The synthesis of a series of different fluorinated analogues of sphinganine and dihydroceramide using Staudinger ligation of diastereomeric 2-azido-4-fluoro-3-hydroxyoctadecanoates and subsequent selective ester reduction as key steps is presented. The formed sphingolipid analogues are interesting for medicinal studies as well as for the investigation of their phase behavior at interfaces. © 2010 Georg Thieme Verlag Stuttgart New York.
- Record ID
- UAM1dd1857ea4c04d3b8db97273fee2eca7
- Author
- Journal series
- Synthesis-Stuttgart, ISSN 0039-7881
- Issue year
- 2010
- Pages
- 3309-3314
- ASJC Classification
- ;
- DOI
- DOI:10.1055/s-0030-1257944 Opening in a new tab
- Language
- (en) English
- Score (nominal)
- 0
- Score source
- journalList
- Publication indicators
- = 4; = 4; : 2014 = 0.694; : 2010 (2 years) = 2.260 - 2010 (5 years) =2.184
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- Uniform Resource Identifier
- https://researchportal.amu.edu.pl/info/article/UAM1dd1857ea4c04d3b8db97273fee2eca7/
- URN
urn:amu-prod:UAM1dd1857ea4c04d3b8db97273fee2eca7
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or PerishOpening in a new tab system.