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Synthesis of Isomeric Dimers of Deoxycholic Acid Derivatives Linked by 1,2,3-Triazole
Authors:
- Iwona Mądrzak-Litwa,
- Anna Aleksandra Wojciechowska-Mrozik,
- Zdzisław Paryzek
Abstract
Steroidal propargylic ester 6 and the propiolic ester 7 were prepared in a few steps from the deoxycholic acid. The Huisgen cycloaddition reaction of alkynes 6 and 7 as dipolarophiles with a 1,3-dipolar compound, the azide 5, afforded the dimeric compounds 8 and 9, respectively, in good yield. The dimers of deoxycholic acid derivatives linked by 1,4-disubstituted 1,2,3-triazole were characterized by spectroscopic methods.
- Record ID
- UAM4f3bfe7fd11c4f5d952b1bb11f05592b
- Author
- Journal series
- Synthetic Communications, ISSN 0039-7911
- Issue year
- 2015
- Vol
- 45
- Pages
- 1222-1230
- ASJC Classification
- DOI
- DOI:10.1080/00397911.2015.1014116 opening in a new tab
- Language
- en English
- Score (nominal)
- 20
- Score source
- journalList
- Score
- Publication indicators
- = 3.000; : 2015 = 0.504; : 2015 = 1.065 (2) - 2015=1.063 (5)
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- Uniform Resource Identifier
- https://researchportal.amu.edu.pl/info/article/UAM4f3bfe7fd11c4f5d952b1bb11f05592b/
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or Perishopening in a new tab system.
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