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Thio analogues of pyrimidine bases: Syntheses and spectral study of new potentially biologically active 2,4-di-ortho-(meta- and para-)bromo- (chloro and nitro)-benzylthio-5-bromouracils (and 6-methyluracils)
Authors:
- Grażyna Barbara Bartkowiak,
- Elzbieta Wyrzykiewicz,
- Grzegorz Marek Schroeder,
- Anna Walkowiak,
- Anna Szponar,
- Ilona Pawlak
Abstract
Eighteen new 2,4-di-ortho- (meta- and para-) bromo-(chloro- and nitro-)benzylthio-5-bromouracils (and 6-methyluracils) have been prepared. The structures of these compounds were confirmed by spectral (IR, UV/vis, 1H NMR) and elemental analyses. Estimation of pharmacotherapeutic potential has been made for synthesized compounds on the basis of prediction of activity spectra for substances (PASS). Copyright © Taylor & Francis Group, LLC.
- Record ID
- UAM51e716bd4fb04ae8b109af7b40f08221
- Author
- Journal series
- Phosphorus Sulfur and Silicon and the Related Elements, ISSN 1042-6507
- Issue year
- 2010
- Vol
- 185
- Pages
- 1429-1436
- ASJC Classification
- ; ;
- DOI
- DOI:10.1080/10426500903061558 Opening in a new tab
- Language
- (en) English
- Score (nominal)
- 0
- Score source
- journalList
- Publication indicators
- = 4; = 5; = 10; : 2014 = 0.344; : 2010 (2 years) = 0.621 - 2010 (5 years) =0.720
- Citation count
- 10
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- Uniform Resource Identifier
- https://researchportal.amu.edu.pl/info/article/UAM51e716bd4fb04ae8b109af7b40f08221/
- URN
urn:amu-prod:UAM51e716bd4fb04ae8b109af7b40f08221
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or PerishOpening in a new tab system.