1H NMR studies of intramolecular hydrogen bonding in N‐(pyridyl)amides of 6‐methylpicolinic acid N‐oxide
Authors:
- Bogumił Brzezinski
Abstract
The 1H NMR spectra of seven N‐(pyridyl)amides of 6‐methylpicolinic acid N‐oxide in chloroform were obtained. The influence on the chemical shifts of the NH protons of temperature, concentration and the CH3 substituent in the pyridine ring was studied. The NH protons were found to be shifted to low fields (∼14 ppm) owing to the formation of strong intramolecular hydrogen bonding. The influence of the pyridine ring on the chemical shift of the NH proton is comparable with the inductive effect of the p‐nitrophenyl group. The hindered rotation around the N‐pyridyl bond of N‐(α‐pyridyl)amides of 6‐methylpicolinic acid in solution is discussed. Copyright © 1979 Heyden & Son Ltd.
- Record ID
- UAM8b7c8015b17f48ac8c6acf7d2a71c2d2
- Author
- Journal series
- Organic Magnetic Resonance, ISSN 0030-4921, e-ISSN 1097-458X
- Issue year
- 1979
- Vol
- 12
- Pages
- 432-434
- DOI
- DOI:10.1002/mrc.1270120709 Opening in a new tab
- Language
- (en) English
- Score (nominal)
- 0
- Score source
- journalList
- Publication indicators
- = 7
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- Uniform Resource Identifier
- https://researchportal.amu.edu.pl/info/article/UAM8b7c8015b17f48ac8c6acf7d2a71c2d2/
- URN
urn:amu-prod:UAM8b7c8015b17f48ac8c6acf7d2a71c2d2
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