Back
Study of penicillin degradation mechanism upon interaction with silver(I) ions
Authors:
- C.N. Banti,
- I. Ketikidis,
- S.K. Hadjikakou,
- A.G. Hatzidimitriou,
- Anita Grześkiewicz,
- Maciej Kubicki,
- N. Hadjiliadis
Abstract
The 4-aminomethylene-2-benzyl-4H-oxazol-5-one (1) and the benzylpenicillic acid (2) were obtained as degraded or re-arranged derivatives of Penicillin G (PenH), which have been treated with silver nitrate. The products were characterized by their melting point, 1H NMR spectroscopy and X-ray crystallography. These alterations might be the etiology of penicillin deactivation.
- Record ID
- UAMeb7de3b64c15484ab1511846a2a3ac9d
- Author
- Journal series
- Inorganica Chimica Acta, ISSN 0020-1693, e-ISSN 1873-3255
- Issue year
- 2020
- Vol
- 509
- Pages
- 1-6
- Article number
- 119683
- Keywords in English
- Biological inorganic chemistry penicillin G degradation Silver(I) acidic pH X-ray structure
- ASJC Classification
- ; ;
- DOI
- DOI:10.1016/j.ica.2020.119683 Opening in a new tab
- URL
- https://www.sciencedirect.com/science/article/abs/pii/S002016932030298X?via%3Dihub Opening in a new tab
- Language
- (en) English
- Score (nominal)
- 70
- Score source
- journalList
- Score
- = 70.0, 13-05-2022, ArticleFromJournal
- Publication indicators
- = 1; = 0; : 2018 = 0.654; : 2019 (2 years) = 2.304 - 2019 (5 years) =1.926
Share
- Uniform Resource Identifier
- https://researchportal.amu.edu.pl/info/article/UAMeb7de3b64c15484ab1511846a2a3ac9d/
- URN
urn:amu-prod:UAMeb7de3b64c15484ab1511846a2a3ac9d
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or PerishOpening in a new tab system.