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The spontaneous rearrangement of 2,4-dinitrophenyl substituent in ribonucleosides under neutral conditions
Authors:
- Anna Olejnik,
- Zofia Gdaniec,
- Elzbieta Kierzek,
- Ryszard Kierzek
Abstract
In the cytidine and adenosine derivatives an isomerization of a 2,4-dinitrophenyl group between the 2'-and 3'-positions of the ribose was observed under neutral conditions. Moreover, it was shown that isomerization of the 2,4-dinitrophenyl group in conditions required to synthesize phosphoramidites and lability in aqueous ammonia make chemical synthesis of 2'-O-(2,4-dinitrophenyl) oligonucleotides impossible. © Taylor and Francis Group, LLC.
- Record ID
- UAMfd7c7fa76fee4284a4c638ffddfca93f
- Author
- Journal series
- Nucleosides Nucleotides & Nucleic Acids, ISSN 1525-7770, [1532-2335]
- Issue year
- 2010
- Vol
- 29
- Pages
- 684-697
- ASJC Classification
- ; ; ;
- DOI
- DOI:10.1080/15257770.2010.507233 Opening in a new tab
- Language
- (en) English
- Score (nominal)
- 0
- Score source
- journalList
- Publication indicators
- = 0; = 0; : 2014 = 0.591; : 2010 (2 years) = 1.132 - 2010 (5 years) =0.784
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- Uniform Resource Identifier
- https://researchportal.amu.edu.pl/info/article/UAMfd7c7fa76fee4284a4c638ffddfca93f/
- URN
urn:amu-prod:UAMfd7c7fa76fee4284a4c638ffddfca93f
* presented citation count is obtained through Internet information analysis and it is close to the number calculated by the Publish or PerishOpening in a new tab system.