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Pulse wave shape analyzing using High Signal Resolution in patients with hypertension

Anna Szymił

Abstract

The aim of the study was to determine the changes in parameters of High Signal Resolution Pulse Wave (HSR-PW) in patients with hypertension in vasodilatatory examination and in nuclear magnetic resonance imaging (NMR). The study analyzed the waveform of the high-definition signal pulse of two groups treated for hypertension (23 and 22 patients). The first group of the subjects of the study were examined with artery FMD and NID vasodilatory tests. FMD test was local and demonstrated the adaptation of the brachial artery to the changes occurring within it. The decrease in the K1/K2 parameter observed 15 seconds after the regression of pressure is caused by an increase in vascular resistance. It is not until after at least one minute, before the maximal diameter of the vessel, is recorded, vascular resistance decreases and the K1/K2 parameter increases. NID test has also exhibited significant changes in the K1/K2 parameter. Its growth in the second minute after receiving nitroglycerin proved a decrease in vascular resistance. In the second group of patients there were compared parameter changes of HSR PW with PWV determined based on NMR. Studies showed that pulse wave velocity of the patients diagnosed with hypertension was higher than in the control group by about 29% and amounted to 8.5 4.2 m/s. The results showed good correlation with K1/K2 parameter. On the basis of the conducted research presented in this paper it can be concluded that the HSR PW pulse wave showed high sensitivity to changes in vascular resistance in patients with arterial hypertension in tests FMD and NID and good correlation with PWV based on nuclear magnetic resonance.
Record ID
UAM1956fcde47254f659c916634b75b5261
Diploma type
Doctor of Philosophy
Author
Title in Polish
Analiza fali pulsu metodą liniowej transformacji u osób z nadciśnieniem tetniczym
Title in English
Pulse wave shape analyzing using High Signal Resolution in patients with hypertension
Language
pol (pl) Polish
Certifying Unit
Faculty of Physics (SNŚ/WyF/FoP)
Discipline
physics / (physical sciences domain) / (physical sciences)
Scientific discipline (2.0)
6.6 physical sciences
Status
Finished
Defense Date
29-10-2015
Title date
29-10-2015
Supervisor
URL
http://hdl.handle.net/10593/13974 Opening in a new tab
Keywords in English
pulse wave, hypertension, pulse wave velocity, vasodilatation test
Abstract in English
The aim of the study was to determine the changes in parameters of High Signal Resolution Pulse Wave (HSR-PW) in patients with hypertension in vasodilatatory examination and in nuclear magnetic resonance imaging (NMR). The study analyzed the waveform of the high-definition signal pulse of two groups treated for hypertension (23 and 22 patients). The first group of the subjects of the study were examined with artery FMD and NID vasodilatory tests. FMD test was local and demonstrated the adaptation of the brachial artery to the changes occurring within it. The decrease in the K1/K2 parameter observed 15 seconds after the regression of pressure is caused by an increase in vascular resistance. It is not until after at least one minute, before the maximal diameter of the vessel, is recorded, vascular resistance decreases and the K1/K2 parameter increases. NID test has also exhibited significant changes in the K1/K2 parameter. Its growth in the second minute after receiving nitroglycerin proved a decrease in vascular resistance. In the second group of patients there were compared parameter changes of HSR PW with PWV determined based on NMR. Studies showed that pulse wave velocity of the patients diagnosed with hypertension was higher than in the control group by about 29% and amounted to 8.5 4.2 m/s. The results showed good correlation with K1/K2 parameter. On the basis of the conducted research presented in this paper it can be concluded that the HSR PW pulse wave showed high sensitivity to changes in vascular resistance in patients with arterial hypertension in tests FMD and NID and good correlation with PWV based on nuclear magnetic resonance.

Uniform Resource Identifier
https://researchportal.amu.edu.pl/info/phd/UAM1956fcde47254f659c916634b75b5261/
URN
urn:amu-prod:UAM1956fcde47254f659c916634b75b5261

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