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Iron oxide nanoparticles in magnetic hyperthermia

Błażej Leszczyński

Abstract

This work deals with the subject of magnetic hyperthermia in magnetic nanoparticles. It refers the topic of linear response theory and its correct application in interpretation of the results of magnetic hyperthermia experiments. This work experimentally shows an unusual relationship of hysteresis loop area varying with AC magnetic field amplitude (previously only simulated numerically for monodispersed nanoparticles). This relationship affects heating efficiency and it was observed in hyperthermia experiment performed on monodispersed nanoparticles. The relationship was not observed earlier mainly because of polidispersity of magnetic fluids. Iron oxide magnetic nanoparticles were synthesized by thermal decomposition method and characterized by TEM, XRD, DLS, SQUID and AC susceptometer. Hyperthermia experiment performed in wide range of frequencies showed different behavior of poly- and monodispersed magnetic fluids. The results of hyperthermia were explained in terms of some fundamental rules.
Record ID
UAMfc83bce4d78549ba9e64cb2207e7ded9
Diploma type
Doctor of Philosophy
Author
Błażej Leszczyński Błażej Leszczyński,, Undefined Affiliation
Title in Polish
Nanocząstki tlenków żelaza w hipertermii magnetycznej
Title in English
Iron oxide nanoparticles in magnetic hyperthermia
Language
pl Polish
Certifying Unit
Faculty of Physics (SNŚ/WyF/FoP)
Discipline
physics / (physical sciences domain) / (physical sciences)
Scientific discipline (2.0)
6.6 physical sciences
Defense Date
06-07-2016
End date
06-07-2016
Supervisor
URL
http://hdl.handle.net/10593/14787 opening in a new tab
Keywords in English
magnetic hyperthermia, ferrofluid, magnetic nanoparticles, iron oxide
Abstract in English
This work deals with the subject of magnetic hyperthermia in magnetic nanoparticles. It refers the topic of linear response theory and its correct application in interpretation of the results of magnetic hyperthermia experiments. This work experimentally shows an unusual relationship of hysteresis loop area varying with AC magnetic field amplitude (previously only simulated numerically for monodispersed nanoparticles). This relationship affects heating efficiency and it was observed in hyperthermia experiment performed on monodispersed nanoparticles. The relationship was not observed earlier mainly because of polidispersity of magnetic fluids. Iron oxide magnetic nanoparticles were synthesized by thermal decomposition method and characterized by TEM, XRD, DLS, SQUID and AC susceptometer. Hyperthermia experiment performed in wide range of frequencies showed different behavior of poly- and monodispersed magnetic fluids. The results of hyperthermia were explained in terms of some fundamental rules.
Thesis file

Uniform Resource Identifier
https://researchportal.amu.edu.pl/info/phd/UAMfc83bce4d78549ba9e64cb2207e7ded9/

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